Large analysis finds that for healthy adults, taking multivitamins daily is not associated with a lower risk of death

A big evaluation of information from almost 400,000 wholesome U.S. adults adopted for greater than 20 years has discovered no affiliation between common multivitamin use and decrease threat of demise. The research, “Multivitamin Use and Mortality Threat in 3 Potential US Cohorts” led by researchers on the Nationwide Institutes of Well being’s Nationwide Most cancers Institute, was printed June 26, 2024, in JAMA Community Open.

Many adults in the USA take multivitamins with the hope of enhancing their well being. Nonetheless, the advantages and harms of standard multivitamin use stay unclear. Earlier research of multivitamin use and mortality have yielded blended outcomes and been restricted by brief follow-up instances.

To extra deeply discover the connection between long-term common multivitamin use and general mortality and demise from heart problems and most cancers, the researchers analyzed information from three massive, geographically numerous potential research involving a complete of 390,124 U.S. adults who have been adopted for greater than 20 years. The individuals included on this evaluation have been usually wholesome, with no historical past of most cancers or different power ailments.

As a result of the research inhabitants was so massive and included prolonged follow-up and intensive data on demographics and way of life elements, the researchers have been capable of mitigate the consequences of doable biases that will have influenced the findings of different research. For instance, individuals who use multivitamins could have more healthy existence generally, and sicker sufferers could also be extra prone to improve their use of multivitamins.

The evaluation confirmed that individuals who took every day multivitamins didn’t have a decrease threat of demise from any trigger than individuals who took no multivitamins. There have been additionally no variations in mortality from most cancers, coronary heart illness, or cerebrovascular ailments. The outcomes have been adjusted for elements corresponding to race and ethnicity, schooling, and food regimen high quality.

The researchers famous that you will need to consider multivitamin use and threat of demise amongst completely different sorts of populations, corresponding to these with documented dietary deficiencies, in addition to the potential impression of standard multivitamin use on different well being circumstances related to growing older.